CELL
THERAPY: THE STATE OF THE ART AND NEW PERSPECTIVES |
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| PAVIA, May 8-10, 2003 - Aula Magna Collegio Ghisleri |
Programma
| 14:30 | Welcome
to the participants (G. Azzaretti, E. Solcia, L. Zambianchi, G. Rondini) |
Modulation
of Immune System by Extracorporeal Photochemotherapy |
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CHAIRPERSONS: |
L. Salvaneschi (Pavia), P. Rebulla (Milano) |
| 15:00-15:30 | ECP
as effective adjunct therapy for adult patients with acute and chronic GVHD
H. Greinix (Wien) |
| 15:30-16:00 | ECP
for treatment of acute and chronic GVHD in children C. Perotti (Pavia) |
| 16:00-16:30 | ECP
for prevention and treatment of rejection in solid organ transplant recipients R. Dall’Amico (Padova) |
| 16:30-17:00 | Biological
predictors of response to ECP M.C. Cuccia, M. Martinetti (Pavia) |
| 17:00-17:30 | Coffee break |
| 17:30-18:00 | Transimmunization:
correcting the flaws of ECP R.L. Edelson (New York) |
| 18:00-18:30 | Simultaneous
clinical scale isolation and expansion of CD4+ and CD8+ virus-specific T
cells using Interferon-gamma secretion J. Campbell (Berdisch, Gladbach) |
| 18:30-19:30 |
Invited lecture introduced by E. Solcia |
BIOETHICAL
ASPECTS OF INNOVATIVE APPROACHES OF HEMATOPOIETIC STEM CELL THERAPY G.R. Burgio (Pavia) |
|
May, 9, 2003
Adoptive
Immunotherapy for Prevention or Treatment of Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation |
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CHAIRPERSONS: |
F. Locatelli (Pavia), M. Martelli (Perugia) |
| 8:30-9:00 | Ex
vivo generation and expansion of human antileukemia CTL lines. D. Montagna (Pavia) |
| 9:00-9:30 | Minor
histocompatibility antigens as targets for immunotherapy after allogeneic
stem cell transplantation F. Falkenburg (Leiden) |
| 9:30-10:00 | Specific
immunotherapy against CML A. Madrigal (London) |
| 10:00-10:30 | Anti-idiotype
vaccination of multiple myeloma and lymphoma patients using ex-vivo generated
dendritic cells R. Lemoli (Bologna) |
| 10:30-11:00 | Coffee break |
| 11:00-11:30 | Impact
of donor NK cell alloreactivity on allogeneic hematopoietic stem cell transplantation A. Velardi (Perugia) |
| 11:30-12:00 | Effects
of granulocyte colony stimulating factor after allogeneic bone marrow transplantation
on engraftment, graft-versus-host disease and survival O. Ringden (Huddinge) |
| 12:00-13:00 | Invited lecture introduced by F. Locatelli |
STEM
CELL TRANSPLANTATION ACROSS MAJOR GENETIC BARRIERS: THE IMMUNO-REGULATORY ROLE OF EARLY HEMATOPOIETIC CELLS Y. Reisner (Rehovot) |
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13.00 |
Lunch |
Adoptive
immunotherapy for prevention or treatment of infectious complications
after allogeneic hematopoietic stem cell or solid organ transplantation |
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CHAIRPERSONS: |
A. Pession (Bologna), G. Gerna (Pavia) |
| 14:30-15:00 | Monitoring
of herpesvirus infections in transplanted patients F. Baldanti (Pavia) |
| 15:00-15:30 | Immunotherapy
of EBV malignancies after hematopoietic stem cell transplantation H. Heslop (Houston) |
| 15:30-16:00 | Immunotherapy
of EBV malignancies after solid organ transplantation P. Comoli (Pavia) |
| 16:00-16:30 | Coffee break |
| 16:30-17:00 | New
strategies to treat CMV infection after allogeneic stem cell transplantation H. Einsele (Tubingen) |
| 17:00-17:30 | Safe
and effective transfer of donor immunity to pathogens across the HLA barrier K. Perruccio (Perugia) |
| 18:00-19:00 | Invited lecture introduced by P. Rebulla |
REGULATORY
ISSUES OF CELL THERAPY G. Migliaccio (Rome) |
|
May, 10, 2003
Adoptive
immunotherapy for induction of tolerance after allogeneic hematopoietic stem cell transplantation |
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CHAIRPERSONS: |
A.P. Bacigalupo (Genova), G. Basso (Padova) |
| 8:30-9:00 | Depletion
of MLC-activated cells combined with CTLA4-Ig treatment as a strategy to
control T-cell mediated alloreactivity R. Maccario (Pavia) |
| 9:00-9:30 | The
infusion of in vitro expanded mesenchimal stem cells reduce the incidence/severity
of GVHD in allogeneic hematopoietic stem cell transplantation F. Frassoni (Genova) |
| 9:30-10:00 | Immunomodulatory
effects of human fetal and adult mesenchymal stem cells K. Le Blanc (Huddinge) |
| 10:00-10:30 | Allodepletion
for haploidentical transplantation: current state for inborn errors M. Cavazzana-Calvo (Paris) |
| 10:30-11:00 | Coffee break |
| 11:00-11:30 | Use
of IL-10 anergyzed T cells in allogeneic bone marrow transplantation M.G. Roncarolo (Milano) |
| 11:30-12:00 | Costimulatory
blockade as a means of decreasing donor anti-host alloreactivity: practice
and theory E. Guinan (Boston) |
| 12:00-12:30 | Human
CD34+ cells induce T cell specific unresponsiveness only under costimulatory
blockade D. Rondelli (Chicago) |
| 12:30- 13:30 | Invited lecture introduced by G.P. Merlini |
ON
CELLULAR BASIS OF IMMUNOLOGICAL MEMORY A. Lanzavecchia (Bellinzona) |
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| 13:30 | Closing remarks |